Conversion of nitrogen dioxide (no2) to nitric oxide (no)
AssigneeVERO Biotech Inc.
InventorsDavid FINE, David Rounbehler, Gregory Vasquez, Bryan Johnson
Life of this patent
Estimating the term…
Abstract
A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
Claims19
1-11. (canceled)
A system for generating a therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal comprising:
- a pressure regulator diffusing gaseous nitrogen dioxide into an air flow;
- and
- a receptacle configured to attach to the pressure regulator, the receptacle capable of converting gaseous nitric dioxide to nitric oxide and including an inlet and an outlet, wherein the inlet is configured to receive the air flow and fluidly communicate the flow to the outlet,
- wherein the system is capable of providing a flow from the outlet of the receptable with a gaseous nitric oxide dose of 5 ppm to 200 ppm without providing toxic amounts of gaseous nitrogen dioxide.
A system for generating a therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal comprising:
- a pressure regulator diffusing gaseous nitrogen dioxide into an air flow;
- and
- a receptacle configured to attach to the pressure regulator, the receptacle capable of converting gaseous nitric dioxide to nitric oxide and including an inlet and an outlet, wherein the inlet is configured to receive the air flow and fluidly communicate the flow to the outlet,
- wherein the system is capable of providing a flow from the outlet of the receptable with a gaseous nitric oxide dose of 200 ppm to 5000 ppm.
Dependencies are inferred from the claim text.