Mesh materials for controlled release of antivirals, method and use

Abstract

Mesh materials for the controlled release of antimicrobial and antiviral compounds, with high antiviral activity and efficacy, predominantly against coronavirus, and a method for producing mesh materials with inclusion compounds of bisbiguanide:cyclodextrin, using mesh materials selected from polymers, fibers, nonwoven fabric, fabrics, paper and cellulose, individually or in combination, or a combination of one or more of these mesh materials with adhesives. The mesh materials impregnated, extruded, saturated, coated or laminated with inclusion compounds have been shown to be effective in the deactivation/destruction of viral particles. In fabrics, the inclusion compounds exhibited virucidal activity for all of the viruses in the coronavirus group for contact times of above 2 minutes, with the effect thereof lasting for more than 30 days. The mesh materials for controlled release of antivirals have displayed activity which is up to 1000 times more effective than the use of unencapsulated chlorhexidine.

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