# US 2023/0266232 A1 · Chromatographic reader devices for biodetection > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2023/0266232 A1 - Document ID: US20230266232A1 - Status: Published application - Kind: A1 - Application number: 18/024,150 - Filed: 2021-08-18 - Published: 2023-08-24 - Earliest claimed: 2020-09-04 - Assignees: 3M Innovative Properties Company - Applicants: 3M Innovative Properties Company - Inventors: Antonia E. Schaefer; Nicholas T. Gabriel; Samuel J. Fahey; Adam C. Nyland; Thaine W. Fuller; John M. Kruse; Nicholas G. Amell; Glendon D. Kappel; Patrick A. Mach - Web page: https://patentgrep.com/patent/US20230266232A1 ## CPC - G01N 21/25: Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands - G01N 21/8483: {Investigating reagent band (test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04)} - G01N 30/90: Plate chromatography, e.g. thin layer or paper chromatography - G01N 2021/6439: {with indicators, stains, dyes, tags, labels, marks} - G01N 2030/8813: {biological materials} - G01N 2201/0221: Portable; cableless; compact; hand-held - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract A device includes camera hardware configured to capture image data associated with an output signal area of a biological chromatographic test strip, and processing circuitry configured to determine, based on the image data, respective intensities of a control line displayed in the output signal area of the biological chromatographic test strip, a hook line displayed in the output signal area of the biological chromatographic test strip, and a test line displayed in the output signal area of the biological chromatographic test strip. The processing circuitry is configured to determine a relative intensity between the test line and at least one of the hook line or control line using the respective intensities, and to detect, based on the relative intensity, a presence of a target analyte in a test sample submitted via the biological chromatographic test strip. ## Claims ### Claim 1 A mobile computing device comprising: camera hardware configured to capture image data associated with an output signal area of a biological chromatographic test strip; processing circuitry in communication with the camera hardware, the processing circuitry being configured to: determine, based on the image data captured by the camera hardware, (i) an intensity of a control line displayed in the output signal area of the biological chromatographic test strip, (ii) an intensity of a hook line displayed in the output signal area of the biological chromatographic test strip, and (iii) an intensity of a test line displayed in the output signal area of the biological chromatographic test strip; determine a relative intensity between the test line and at least one of the hook line or control line using the intensity of the test line and at least one of the intensity of the hook line or the intensity of the control line; and detect, based on the relative intensity, a presence of a target analyte in a test sample submitted via the biological chromatographic test strip. ### Claim 2 (depends on 1) The mobile computing device of claim 1, the processing circuitry being further configured to determine, based on the relative intensity, a concentration of the target analyte in the test sample submitted via the biological chromatographic test strip. ### Claim 3 (depends on 1) The mobile computing device of claim 1, wherein the respective intensities of the control line, the hook line, and the test line represent colorimetric intensities. ### Claim 4 (depends on 3) The mobile computing device of claim 3, wherein the colorimetric intensities represent intensities along individual color channels of an RGB color space. ### Claim 5 (depends on 1) The mobile computing device of claim 1, wherein the mobile computing device is a smartphone. ### Claim 6 (depends on 5) The mobile computing device of claim 5, wherein the camera hardware is included in a rear-facing camera of the smartphone. ### Claim 7 (depends on 5) The mobile computing device of claim 5, wherein the camera hardware is included in a front-facing camera of the smartphone. ### Claim 8 (depends on 1) The mobile computing device of claim 1, wherein the mobile computing device is a tablet computer. ### Claim 9 (depends on 1) The mobile computing device of claim 1, wherein the mobile computing device is a wearable device. ### Claim 10 (depends on 1) The mobile computing device of claim 1, wherein the interface is a touchscreen display. ### Claim 11 A mobile computing device comprising: camera hardware configured to capture image data associated with an output signal area of a biological chromatographic test strip; processing circuitry in communication with the camera hardware, the processing circuitry being configured to determine, based on the image data captured by the camera hardware, a concentration of a target analyte in a test sample submitted via the biological chromatographic test strip; and an interface in communication with the processing circuitry, the interface being configured to output data indicative of the concentration of the target analyte determined by the processing circuitry. ### Claim 12 (depends on 11) The mobile computing device of claim 11, wherein to determine the concentration of the target analyte in the test sample, the processing circuitry is configured to: determine, based on the image data captured by the camera hardware, (i) an intensity of a control line displayed in the output signal area of the biological chromatographic test strip, (ii) an intensity of a hook line displayed in the output signal area of the biological chromatographic test strip, and (iii) an intensity of a test line displayed in the output signal area of the biological chromatographic test strip; determine a relative intensity between the test line and at least one of the hook line or control line using the intensity of the test line and at least one of the intensity of the hook line or the intensity of the control line; and determine the concentration of the target analyte based on the relative intensity. ### Claim 13 (depends on 11) The mobile computing device of claim 11, wherein the mobile computing device is a smartphone. ### Claim 14 (depends on 13) The mobile computing device of any of claim 13, wherein the camera hardware is included in one of a rear-facing camera of the smartphone or a front-facing camera of the smartphone. ### Claim 15 (depends on 10) The mobile computing device of claim 10, wherein the interface is a touchscreen display.