# US 2023/0265262 A1 · Method of visualizing, monitoring polymerization, and isolating plastic product produced by polymerization of resin with proton beams > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2023/0265262 A1 - Document ID: US20230265262A1 - Status: Published application - Kind: A1 - Application number: 17/933,132 - Filed: 2022-09-19 - Published: 2023-08-24 - Earliest claimed: 2022-02-22 - Inventors: George Edward Parris - Web page: https://patentgrep.com/patent/US20230265262A1 ## CPC - C08K 3/30: Sulfur-, selenium- or tellurium-containing compounds - C08K 2003/3036: {of zinc} - C08K: Use of inorganic or non-macromolecular organic substances as compounding ingredients (paints, inks, varnishes, dyes, polishes, adhesives C09) ## Abstract A method for isolating plastic products produced by polymerization of resin with proton beams is disclosed. The method comprises a liquid resin added with a reactive dye that changes from transparent or colorless to color when activated by the proton beam or the chemical polymerization process to reveal polymerization within a polymerizable resin. The change in color is correlated to the energy delivered to the resin by a proton beam, electromagnetic radiation, or heat. The reactive dye is placed into a plastic container. The proton beam is directed into the container to polymerize the resin. When irradiation is complete, the container of frozen resin is opened at the top and bottom and placed on top of the column of water containing a density gradient provided by dissolved salt. The partially cured product is fully cured while suspended in the density gradient by application of heat or ultraviolet radiation. ## Claims ### Claim 1 A method for isolating plastic products produced by polymerization of resin with proton beams, comprising the step of: adding reactive dyes into a liquid resin in a container, and directing proton beams into the container to polymerize the liquid resin, thereby the reactive dye changes from transparent or colorless to color when activated by the proton beams. ### Claim 2 (depends on 1) The method of claim 1, wherein the polymerizable resin is an acrylic resin. ### Claim 3 (depends on 1) The method of claim 1, wherein the polymerizable resin reacts by a free radical or ionic mechanism. ### Claim 4 (depends on 1) The method of claim 1, wherein the reactive dye is leuco-crystal violet (LCV). ### Claim 5 (depends on 1) The method of claim 1, wherein the change in color is correlated to the energy delivered to the resin by one of the proton beam, electromagnetic radiation, or heat. ### Claim 6 A method for isolating plastic products formed in situ of the liquid resin comprising the step of, introducing a dense immiscible liquid to displace the residual liquid resin. ### Claim 7 (depends on 6) The method of claim 6, wherein the liquid resin is modified by adding a miscible liquid that changes the density of the resin phase. ### Claim 8 (depends on 6) The method of claim 6, wherein the dense immiscible liquid is introduced from the bottom of the container. ### Claim 9 (depends on 6) The method of claim 6, wherein the dense immiscible liquid is a solution of an inorganic salt in water. ### Claim 10 (depends on 6) The method of claim 6, wherein the dense immiscible liquids are in contact as the product is formed in the resin phase. ### Claim 11 (depends on 6) The method of claim 6, wherein the dense immiscible liquids are frozen during the formation of the product in situ. ### Claim 12 (depends on 6) The method of claim 6, wherein the residual resin recovered from density gradient separation is recycled or reused. ### Claim 13 (depends on 6) The method of claim 6, further includes the step of: placing a low-density organic solvent atop on an aqueous solution to expedite the separation of organic liquids. ### Claim 14 (depends on 6) The method of claim 6, further includes the step of: exposing a partially cured semi-solid product to electromagnetic radiation or heat while it is suspended in a density gradient. ### Claim 15 A proton beam energy deposition method to detrain the radiation absorbed using a container, comprising the step of: depositing of energy within a stable matrix with a proton beam; activating one or more redox indicators incorporated into the stable matrix or container when the volume is affected by the energy deposition; and indicating a two-dimensional concept of energy deposition along the beam using a graph; wherein the redox indicator within the stable matrix provides a three-dimensional image of the deposition of energy of ionizing radiation within the matrix, and the graph includes an indication of the threshold level to produce a viewable change in the redox indicator, and wherein the container includes a graduated marking along the sides to readily determine the extent and location of color change in the matrix. ### Claim 16 (depends on 15) The method of claim 15, wherein the matrix is composed of transparent gelatin, wax, plastic, or liquid resin that may be either free-standing or contained in a transparent container. ### Claim 17 (depends on 15) The method of claim 15, wherein the redox indicator includes one or more compounds composed of elements with atomic numbers less than 10. ### Claim 18 (depends on 15) The method of claim 15, in which the ionizing radiation is a proton beam or high energy electromagnetic radiation. ### Claim 19 (depends on 15) The method of claim 15, wherein the redox indicator is measured quantitatively by absorption spectroscopy to provide a quantitative image of the dose or radiation delivered to the matrix in each voxel or pixel. ### Claim 20 (depends on 19) The method of claim 19, wherein the quantitative images are used for planning or evaluating dosimetry in treating cancer tumors, medical interventions, or designing additive manufacturing programs. ### Claim 21 (depends on 15) The method of claim 15, wherein finely divided zinc sulfide with or without an activating agent such as Ag or Au doping is suspended in the resin in order to generate short wavelength (less than 400 nm) electromagnetic radiation by scintillation when struck by high energy protons to activate the resin to polymerization.