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US 2023/0256074 A1Published application
Vaccines against african swine fever virus, and methods of using same
AssigneeThe Wistar Institute of Anatomy and Biology
InventorsKar Muthumani, David Weiner
Life of this patent
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Abstract
An aspect of the present invention is related to nucleic acid constructs capable of expressing at least one African swine fever virus (ASFV) antigen that elicits an immune response in a mammal against ASFV virus, and methods of use thereof.
Claims20
A nucleic acid molecule comprising a nucleotide sequence encoding at least one synthetic African swine fever virus (ASFV) antigen.
A peptide comprising at least one amino acid sequence selected from the group consisting of
- a) an amino acid sequence having at least about 90% identity over an entire length of the amino acid sequence selected from the group consisting of SEQ ID NO:26, SEQ ID NO:28, SEQ ID NO:22, SEQ ID NO:24 and SEQ ID NO:30,
- b) an immunogenic fragment comprising at least about 90% identity over at least 60% of the amino acid sequence selected from the group consisting of SEQ ID NO:26, SEQ ID NO:28, SEQ ID NO:22, SEQ ID NO:24 and SEQ ID NO:30,
- c) the amino acid sequence selected from the group consisting of SEQ ID NO:26, SEQ ID NO:28, SEQ ID NO:22, SEQ ID NO:24 and SEQ ID NO:30, and
- d) an immunogenic fragment comprising at least 60% of the amino acid sequence selected from the group consisting of SEQ ID NO:26, SEQ ID NO:28, SEQ ID NO:22, SEQ ID NO:24 and SEQ ID NO:30.
1 more element
Dependencies are inferred from the claim text.