US 2023/0235271 A1 · MICROORGANISM PRODUCING EICOSAPENTAENOIC ACID AND METHOD FOR PRODUCING EICOSAPENTAENOIC ACID

Abstract

An object of the present invention is to provide a microorganism that efficiently produces EPA and a method for producing EPA using the microorganism. The present invention relates to a microorganism having an ability to produce docosahexaenoic acid (DHA), wherein the microorganism contains a protein composed of an amino acid sequence in which at least one of the amino acid residues at positions 6, 65, 230, 231, and 275 in the amino acid sequence represented by SEQ ID NO: 2 has been substituted with another amino acid residue (mutated OrfB), and is capable of producing eicosapentaenoic acid (EPA), and the like.

Claims7

Dependent claims

A microorganism having an ability to produce docosahexaenoic acid (DHA), wherein the microorganism contains a mutated OrfB homolog protein that is a homolog of a protein composed of an amino acid represented by SEQ ID NO:

2, except that at least one of the amino acid residues corresponding to amino acids at positions 6, 65, 230, 231, and 275 in SEQ ID NO:
2 has been substituted with another amino acid residue, and wherein the mutated OrfB homolog protein gives the microorganism an ability to produce eicosapentaenoic acid (EPA).

Dependencies are inferred from the claim text.

Facts

Application

18/169,487Filed 15 Feb 2023

Priority

JP 2018-15123410 Aug 2018

Published

27 Jul 2023

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

C12N 1/105
Protozoa; Culture media therefor: protozoal isolates
C12N 9/001
Oxidoreductases: acting on the CH-CH group of donors
C12N 9/1029
Acyltransferases: transferring groups other than amino-acyl groups
C12N 15/52
DNA or RNA fragments; Modified forms thereof ; Non-coding nucleic acids having a biological activity: genes encoding for enzymes or proenzymes

Microorganism producing eicosapentaenoic acid and method for producing eicosapentaenoic acid

Life of this patent

Microorganism producing eicosapentaenoic acid and method for producing eicosapentaenoic acid

Life of this patent

Abstract

Claims7