Method for judging risk of suffering kidney cancer
AssigneesChang Gung University, Chang Gung Memorial Hospital, Linkou
InventorsYI-TING CHEN, RONG-SHING CHANG, YU CHANG, CHIEN-LUN CHEN, KAI-JIE YU, YING-HSU CHANG
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Abstract
The invention relates to a method for judging risk of suffering kidney cancer. The method includes detecting a PSMB9 protein concentration value from a test sample. And a risk factor value is obtained after processing the PSMB9 protein concentration value with an age. When the score of the risk factor value is greater than a defined threshold value of the risk factor threshold value, then the test sample is classified as a high risk sample of a of potential kidney cancer patient.
Claims11
A method of judging a risk of suffering kidney cancer, includes the steps of:
- obtaining a test sample;
- detecting a PSMB9 protein in the test sample to obtain a PSMB9 protein concentration value, in which the PSMB9 protein has the amino acid sequence of SEQ ID NO:
- 1;
- the PSMB9 protein concentration value to obtain a value of a risk factor;
- comparing the value of the risk factor with a threshold value of the risk factor;
- and
- when the value of the risk factor is greater than the threshold value of the risk factor, judge that the test sample has a high risk of suffering kidney cancer;
- wherein the threshold value of the risk factor is 0.037 (fmol PSMB9/μg urine protein).
A method of judging a risk of suffering kidney cancer, includes the steps of:
- obtaining a test sample;
- detecting a PSMB9 protein in the test sample to obtain a PSMB9 protein concentration value, in which the PSMB9 protein has the amino acid sequence of SEQ ID NO:
- 1;
- multiplying the PSMB9 protein concentration value by an age to obtain a value of a first risk factor;
- comparing the value of the first risk factor with a threshold value of the first risk factor;
- and when the value of the first risk factor is greater than the threshold value of the first risk factor, judge that the test sample has a high risk of suffering kidney cancer;
- wherein the threshold value of the first risk factor is 2.687 (fmol/μg*age).
A method of judging a risk of suffering kidney cancer, includes the steps of:
- obtain a test sample;
- detecting a PSMB9 protein in the test sample to obtain a PSMB9 protein concentration value, in which the PSMB9 protein has the amino acid sequence of SEQ ID NO:
- 1;
- dividing the PSMB9 protein concentration value by an age to obtain a value of a second risk factor;
- comparing the value of the second risk factor with a threshold value of the second risk factor;
- and
- when the value of the second risk factor is greater than the threshold value of the second risk factor, judge that the test sample has a high risk of suffering kidney cancer;
- wherein the threshold value of the second risk factor is 0.00032 [(fmol/μg)/age].
A method of judging a risk of suffering kidney cancer;
- includes the steps of:
- obtaining a post-operative test sample;
- the post-operative test sample is taken from a test subject that has undergone a medicine treatment or a surgical treatment or a combination of both;
- detecting a PSMB9 protein in the post-operative test sample to obtain a PSMB9 protein concentration value, the PSMB9 protein has the amino acid sequence of SEQ ID NO:
- 1;
- multiplying the PSMB9 protein concentration value by an age to obtain a value of a third risk factor;
- comparing the value of the third risk factor with a threshold value of the third risk factor;
- and
- when the value of the third risk factor is greater than the threshold value of the third risk factor, judge that the post-operative test sample has a high risk of suffering kidney cancer;
- wherein the threshold value of the third risk factor is 2.687 (fmol/μg*age).
A method of judging a risk of suffering kidney cancer;
- include the steps of:
- obtaining a post-operative test sample, the post-operative test sample is taken from a test subject that has undergone a medicine treatment or a surgical treatment or a combination of both;
- detecting a PSMB9 protein in the post-operative test sample to obtain a PSMB9 protein concentration value;
- the PSMB9 protein has the amino acid sequence of SEQ ID NO:
- 1;
- dividing the PSMB9 protein concentration value by an age to obtain a value of a fourth risk factor;
- comparing the value of the fourth risk factor with a threshold value of the fourth risk factor;
- and
- when the value of the fourth risk factor is greater than the threshold value of the fourth risk factor, judge that the post-operative test sample has a high risk of suffering kidney cancer;
- wherein the threshold value of the fourth risk factor is 0.00032 [(fmol/μg)/age].
Dependencies are inferred from the claim text.