Adjustment Of Target Interface Position In A Centrifuge Based On Lipid Concentration

A blood separation system, comprising:

• a blood separation chamber configured to process blood to separate at least one cellular component from plasma;
• an input device for providing a lipid concentration within the blood to be processed;
• a pump for moving the plasma;
• an outlet line associated with the blood separation chamber for removing at least a portion of the plasma from the blood separation chamber;
• an optical sensor assembly configured to directly monitor the interior of the blood separation chamber and to measure an interface position between the separated component and the plasma, and to generate an output indicative of the measured interface position;
• and
• a controller programmed to receive the lipid concentration within the blood from the input and to set an original lipemia offset, a lipemia threshold and lipemia final setpoint from a predetermined database, wherein the setpoint equals an ideal interface position that would be required to achieve acceptable separation efficiency of plasma without lipids plus the original lipemia offset, wherein the controller is further programmed with a proportional-integral-derivative control loop to continue to measure the interface position and to assess whether the actual interface position is greater than the ideal interface position plus the lipemia threshold, wherein the controller continues said measuring and assessing until the setpoint equals the final lipemia setpoint.