Chemical composition
AssigneesThe University of Liverpool, The Johns Hopkins University
InventorsSteven Paul Rannard, Andrew Owen, Alison Savage, Lee Tatham, Theresa Shapiro, Rahul P. Bakshi, Godfree Mlambo, Abhai Tripathi
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Abstract
A solid composition comprising nanoparticles of atovaquone dispersed within one or more carrier materials, wherein the atovaquone is present in an amount of at least 10 wt %. Also described is an intramuscularly- or subcutaneously-injectable formulation of nanoparticles of atovaquone.
Claims38
A solid composition comprising nanoparticles of atovaquone dispersed within one or more carrier materials, wherein the atovaquone is present in an amount of at least wt %.
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An intramuscularly-injectable or subcutaneously-injectable formulation of nanoparticles of atovaquone.
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A dispersion comprising atovaquone in a concentration of at least 10 mg/mL, which is:
- (i) an aqueous dispersion, comprising a plurality of nanoparticles of atovaquone dispersed in an aqueous medium, each nanoparticle of atovaquone being a core around at least some of which an outer layer composed of one or more carrier materials is provided;
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- (ii) an oily dispersion, comprising a plurality of nanoparticles of atovaquone and one or more carrier materials dispersed in an oily medium.
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Dependencies are inferred from the claim text.