Screening method for laminin 511 production promoting agent, basal epidermal layer stabilizing agent, and/or epidermal stem cells reduction inhibiting or proliferation promoting agent
AssigneeShiseido Company, Ltd.
InventorsShunsuke IRIYAMA, Saori TANNO
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Abstract
The purpose of this invention is to provide a method with which it is easy to perform screening for an agent that proliferates or an agent that minimizes the reduction in MCSP-positive basal epidermal stem cells. Provided is a screening method for a laminin 511 expression promoter, which takes the expression of laminin 511 as an indicator. Also provided is an agent for improving skin barrier function, elasticity, hydration and inflammation, said agent including at least one extract selected from among a group consisting of brown algae, red algae and green algae.
Claims17
A method for inhibiting an activity of an extracellular matrix degrading enzyme, comprising administering 1-(2-hydroxyethyl)-2-imidazolidinone to a subject in need thereof, wherein said administering inhibits the activity of the extracellular matrix degrading enzyme in the subject.
Dependencies are inferred from the claim text.