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AssigneeModeX Therapeutics, Inc.
InventorsRonnie Rong WEI, Ling XU, Zhi-Yong YANG, Edward SEUNG, Gary J. NABEL, Lan WU, Mark GRECI, Hao CHEN
Estimating the term…
Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, chimeric antigen receptors (CARs), immune cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes.
1-127. (canceled)
An antigen binding polypeptide complex comprising a first polypeptide and a second polypeptide;
An antigen binding polypeptide complex comprising a first polypeptide and a second polypeptide;
A polypeptide having at least 95% identity to any one of SEQ ID NOs:32-43, 62-79, 130-138, 633, 635, 637, 639, 641, 643, 645, 647, 649, 651, 653, 655, 657, 659, 661, 663, 665, 667, 669, 671, 673, 675, 677, and 679, or having at least 95% identity to the amino acid sequence of SEQ ID NOs:32 or 33 that does not contain the eight histidine residues at the C-terminus.
A polynucleotide having at least 95% identity to any one of SEQ ID NOs:44-55, 80-97, 139-147, 634, 636, 638, 640, 642, 644, 646, 648, 650, 652, 654, 656, 658, 660, 662, 664, 666, 668, 670, 672, 674, 676, 678, and 680.
Dependencies are inferred from the claim text.