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US 2023/0190642 A1Published application
Growth factor otic formulations
AssigneeOtonomy, Inc.
InventorsFabrive PIU, Bonnie JACQUES, Natalia TSIVKOVSKAIA, Hong QI, Robert SAVEL, Scott COLEMAN, Zhanpeng ZHANG, Martha PASTUSZKA
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Abstract
Disclosed herein are otic formulations and compositions comprising growth factors. These otic formulations and compositions allow for the delivery of the growth factor to the outer, middle, and/or inner ear for the treatment of otic diseases and disorders.
Claims28
An otic formulation comprising a therapeutically effective amount of a growth factor and an auris-acceptable vehicle, wherein the otic formulation is formulated to provide sustained release of the growth factor into the inner ear to promote formation of synapses.
Dependencies are inferred from the claim text.