Cells and methods for producing methyl ketones
AssigneeWisconsin Alumni Research Foundation
InventorsBrian F. Pfleger, Qiang Yan, Trevor R. Simmons, Nestor Hernandez-Lozada
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Abstract
Recombinant cells and methods for producing methyl ketones, such as medium-chain methyl ketones. The recombinant cells include recombinant acyl-ACP thioesterase genes, recombinant β-ketoacyl-CoA thioesterase genes, and recombinant acyl-CoA synthetase genes, in addition to other modifications. The methods include culturing the recombinant cells to produce the methyl ketones and isolating the produced methyl ketones.
Claims25
A recombinant cell for producing methyl ketones comprising:
- a recombinant β-ketoacyl-CoA thioesterase gene;
- a recombinant acyl-ACP thioesterase gene;
- and
- a recombinant acyl-CoA synthetase gene.
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