Recombinant viruses, insect cells and their uses in viral detection and vaccination
AssigneeAcademia Sinica
InventorsYu-Chan CHAO, Sung-Chan WEI, Huei-Ru LO, Chih-Hsuan TSAI, Yu-Wen LO, Wei-Ting HSU, Chuan-Yu LIAO
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Abstract
Disclosed herein are recombinant viruses and/or insect cells suitable for detecting the infection of a pathogen in a biological sample of a test subject. The information derived from the detection may also be used to render a diagnosis on whether the test subject is infected with the pathogen or not, so that proper course of treatment may be assigned to the subject. Also disclosed herein is a vaccine for the prophylaxis and/or treatment of infection caused by said pathogen.
Claims17
A recombinant baculovirus comprising a promotor, and a first nucleic acid operably linked to the promoter, wherein the nucleic acid encodes S or N protein of a coronavirus to be expressed on the outer surface of the recombinant virus.
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Dependencies are inferred from the claim text.