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US 2023/0158044 A1Published application
Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
AssigneeFerring B.V.
InventorsSalah U. Ahmed, Jiaxiang TSAO, Anu MAHASHABDE, Diane D. HARRISON
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Abstract
The present invention relates to monolithic intravaginal rings comprising progesterone, methods of making, and uses thereof. The intravaginal rings comprise progesterone, a polysiloxane elastomer, and a pharmaceutically acceptable hydrocarbon or glycerol esters of a fatty acid.
Claims19
1-52. (canceled)
A monolithic intravaginal ring for treating a luteal phase defect in a patient in need thereof, comprising:
- (a) about 15% to about 30% by weight of progesterone;
- (b) about 55% to about 90% by weight of polysiloxane elastomer;
- and
- (c) about 1% to about 10% by weight of a pharmaceutically acceptable hydrocarbon or glycerol esters of a fatty acid or pharmaceutically acceptable oil, wherein the progesterone is homogeneously dispersed in the elastomer.
1 more element
Dependencies are inferred from the claim text.