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US 2023/0149919 A1Published application
Cassette for preservation of natural and bioengineered tissues
AssigneeTissue Testing Technologies LLC
InventorsLia H. CAMPBELL, Gregory J. WRIGHT, Elizabeth GREENE, Kelvin G.M. BROCKBANK
Life of this patent
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Abstract
Described herein are cassettes and methods for using these cassettes for cryopreserving biomaterials (e.g., a bioengineered construct or natural tissue sample) by vitrification while reducing or preventing the loss of viability associated with conventional preservation methods.
Claims23
A multi-sample cassette comprising:
- a first part and a second part that are configured to fit together via a releasable locking mechanism, the second part comprising one or more inserts and a plurality of place holders, each place holder of the plurality of place holders being configured to receive one of the one or more inserts, wherein
- each of the one or more inserts comprising at least one bioengineered construct or natural tissue sample,
- the first part and the second part comprise a plurality of apertures configured to allow a solution to flow through and around each of the one or more inserts and the at least one bioengineered construct or natural tissue sample, and
- the configuration of the place holders within the cassette is set up to mimic the configuration of wells in a plate having a predetermined number of wells, predetermined number of wells being in the range of from 6 to 384 wells.
1 more element
Dependencies are inferred from the claim text.