Use of mouse model in evaluation of intelligence level
AssigneeGempharmatech Co., Ltd.
InventorsCunxiang JU, Jing ZHAO, Jingjing WANG, Zhong CHEN
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Abstract
A mouse model may be used in evaluation of the change in intelligence level. The mouse model may be a mouse model with high intelligence level. The mouse chromosome of the mouse model with high intelligence level at least includes all or a portion of chromosome 1 originated from wild-type mouse. The evaluation includes performing a test which may be an open field test, sucrose preference test, water maze test, space exploration Y maze test, active avoidance Y maze test, and/or fatigue rotarod test.
Claims10
A method of preparing a system for identifying drug candidates for preventing and/or treating one or more diseases related to intelligence level, the method comprising:
- employing a mouse model with high intelligence level,
- wherein a mouse chromosome of the mouse model with high intelligence level originating from Strain C57BL/6J, at least comprises all or a portion of chromosome 1 originated from wild-type mouse.
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Dependencies are inferred from the claim text.