Composition for cancer prevention or treatment, containing, as active ingredient, salvianolic acid b or tanshinone i
AssigneeGjmedi Inc.
InventorsSe Bok JANG, Mi Suk JEONG, Chang Woo HAN
Life of this patent
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AssigneeGjmedi Inc.
InventorsSe Bok JANG, Mi Suk JEONG, Chang Woo HAN
Estimating the term…
The present invention relates to a composition for cancer prevention or treatment, containing, as an active ingredient, salvianolic acid B or tanshinone I. Specifically, provided are a pharmaceutical composition and a health functional food composition for KRAS-mutated cancer prevention or treatment, the compositions containing, as an active ingredient, salvianolic acid B or tanshinone I. Compared to a conventional therapeutic agent, salvianolic acid B or tanshinone I strongly binds to KRAS mutants so as to have an improved ability to target cancer cells induced by KRAS mutations, and thus diseases that are refractory to treatment with existing therapeutic agents, such as cancer in which KRAS mutations are overexpressed, can be effectively treated.
A method of preventing or treating KRAS-mutated cancer in a subject in need thereof, comprising:
6-8. (canceled)
A method of suppressing expression of KRAS mutation, comprising treating an animal other than humans with salvianolic acid B or tanshinone I.
A method of inhibiting proliferation of cancer cells induced by KRAS mutation, comprising treating an animal other than humans with salvianolic acid B or tanshinone I.
Dependencies are inferred from the claim text.