Method for prognosis prediction of skin cancer and use thereof
AssigneePublic University Corporation Nagoya City University
InventorMotoki NAKAMURA
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Abstract
Provided is a technique of predicting prognosis of skin cancer. A method for prognosis prediction of skin cancer includes: a step of obtaining a correlation amount correlated with an expression level of a glucose-6-phosphate dehydrogenase in a sample collected from a patient with the skin cancer; and a step of determining that the prognosis of the skin cancer is poorer when the correlation amount is large than that when the correlation amount is small.
Claims12
A method for prognosis prediction of skin cancer, comprising:
- a step of obtaining a correlation amount correlated with an expression level of a glucose-6-phosphate dehydrogenase in a sample collected from a patient with the skin cancer;
- and
- a step of determining that the prognosis of the skin cancer is poorer when the correlation amount is large than the prognosis of the skin cancer when the correlation amount is small.
An evaluation method for evaluating effectiveness of an immune checkpoint inhibitor against skin cancer, comprising:
- a step of obtaining a correlation amount correlated with an expression level of a glucose-6-phosphate dehydrogenase in a sample collected from a patient with the skin cancer;
- and
- a step of evaluating that the effectiveness of the immune checkpoint inhibitor is higher when the correlation amount is small than the effectiveness of the immune checkpoint inhibitor when the correlation amount is large.
A method for evaluating malignancy of skin cancer, comprising:
- a step of obtaining a correlation amount correlated with an expression level of a glucose-6-phosphate dehydrogenase in a sample collected from a patient with the skin cancer;
- and
- a step of determining that the malignancy of the skin cancer is higher when the correlation amount is large than the malignancy of the skin cancer when the correlation amount is small.
10-15. (canceled)
A measurement kit,
- the measurement kit being used in at least one of prognosis prediction of skin cancer, evaluation of effectiveness of an immune checkpoint inhibitor against the skin cancer, evaluation of malignancy of the skin cancer, prediction of recurrence of the skin cancer, prediction of a the immune checkpoint inhibitor, and evaluation of an immune activity of the skin cancer,
- the measurement kit comprising a substance capable of detecting a correlation amount correlated with an expression level of a glucose-6-phosphate dehydrogenase in a sample collected from a patient with the skin cancer.
Dependencies are inferred from the claim text.