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US 2023/0146072 A1Published application
Anti-gucy2c antibodies and uses thereof
AssigneePfizer Inc.
InventorsChew Shun CHANG, Divya MATHUR, Adam Reid ROOT
Life of this patent
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Abstract
The present invention is directed to antibodies that specifically bind to GUCY2c and methods of using such antibodies in the diagnosis and/or treatment of cancer.
Claims32
An isolated antibody that specifically binds to Guanylyl cyclase C (GUCY2c) and comprises:
- a heavy chain variable region (VH) comprising a VH complementarity determining region one (CDR1), VH CDR2, and VH CDR3 of the amino acid sequence shown in SEQ ID NO:
- 2.
- a light chain variable region (VL) comprising a VL CDR1, VL CDR2, and VL CDR3 of the amino acid sequence shown in SEQ ID NO:
- 1.
1 more element
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Dependencies are inferred from the claim text.