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US 2023/0145478 A1Published application
Isoflavonoid compounds and methods for the treatment of cancer
AssigneeMEI Pharma, Inc.
InventorsGeorge JEOFFREYS, Alison JOHNSON, Andrew HEATON, Ofir MORENO
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Abstract
Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in cancer cells by administering such compositions.
Claims15
A pharmaceutical composition comprising a compound of formula II or a pharmaceutically acceptable salt thereof:
- wherein
- R1 is hydroxy, alkoxy, haloalkyl, or halo;
- R2 is hydroxy or alkoxy;
- R3 is alkyl, halo, or haloalkyl;
- R4, R5, and R6 are independently hydrogen, hydroxy, alkoxy, halo, haloalkyl, or alkyl;
- and
- R7 is alkyl or hydrogen.
4 more elements
A pharmaceutical composition comprising a compound of formula IV or a pharmaceutically acceptable salt thereof:
- wherein
- R8 is hydrogen.
Dependencies are inferred from the claim text.