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AssigneesAalto University Foundation sr, Helsingin Yliopisto
InventorsChristopher JONKERGOUW, Ekaterina OSMEKHINA, Markus LINDER, Katarzyna LESKINEN, Päivi SAAVALAINEN
Estimating the term…
This invention relates to use of a macrocyclic cavity-containing compound sensitizing a microbe towards an antimicrobial agent. The invention also relates to use of a macrocyclic cavity-containing compound in reducing the amount of an antimicrobial agent needed to prevent or inhibit the growth of a microbe in a subject. Further, the invention relates to use of a macrocyclic cavity-containing compound in reducing the build-up of resistance of a microbe towards an anti-microbial agent. The invention also relates to a macrocyclic cavity-containing compound and an antimicrobial agent for use in inhibiting/treating/preventing a microbial infection in a subject having a microbial infection or being at risk of a microbial infection.
1-9. (canceled)
A method of sensitizing a microbe or reducing build-up of resistance of a microbe towards an antimicrobial agent by exposing the microbe to a macrocyclic cavity-containing compound and the antimicrobial agent.
-14. (canceled)
A method of inhibiting and/or treating and/or preventing a microbial infection in a subject having a microbial infection or being at risk of a microbial infection or formation of a biofilm by a microbe in the subject by administering an antimicrobial agent and a macrocyclic cavity-containing compound to the subject.
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-22. (canceled)
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-29. (canceled)
-35. (canceled)
Dependencies are inferred from the claim text.