Device with insert plug for occluding the left atrial appendage

An occlusion device for implantation in a left atrial appendage, the occlusion device comprising:

• a proximal hub defining a recess;
• a frame connected to the proximal hub and extending distally therefrom, the frame configured to move between a radially collapsed delivery configuration and a radially expanded configuration for engaging an interior wall of the left atrial appendage;
• a membrane coupled to and covering at least a proximal portion of the frame, the membrane comprising a material configured to block a passage of blood clots therethrough;
• and
• a plug disposed within the recess in the proximal hub and configured to releasably couple with a distal end of a delivery shaft, the plug configured to move between a first position at a distal end of the recess during delivery and a second position at a proximal end of the recess after the delivery shaft is disconnected, the plug configured to remain in the recess after removal of the delivery shaft.

A system for implanting an occlusion device in a left atrial appendage, the system comprising:

• a flexible delivery catheter;
• a delivery shaft extending through the delivery catheter;
• and
• an occlusion device comprising:
• a proximal hub defining a recess configured to releasably connect with the delivery catheter;
• a frame connected to the proximal hub and extending radially and then distally from the proximal hub, the frame having a proximal portion, an intermediate portion, and a distal portion, the frame comprising a plurality of struts extending between the proximal portion the distal portion;
• a membrane coupled to and covering at least the proximal portion of the frame, the membrane comprising a material configured to block a passage of blood clots therethrough;
• a plug configured to be received in the recess and remain in the recess after implantation, the plug having a first connection element on a proximal end thereof;
• wherein the delivery shaft has a second connection element on a distal end thereof, the second connection element configured to releasably engage the first connection element on the plug.