Compounds and uses thereof

A compound having the structure:

• wherein
• A is
• m is 0, 1, 2, or 3;
• n is 1 or 2;
• o is 0 or 1;
• X is O, CH2, or NR7;
• X′ is N, CH, or CRX, wherein RX is a halogen;
• B is an optionally substituted 6-membered monocyclic heteroarylene or an optionally substituted 9- or 10-membered bicyclic heteroarylene;
• L is a covalent bond, optionally substituted C1-C3 alkylene, C2 alkynylene, optionally substituted C2 alkenylene, optionally substituted C2-C3 heteroalkylene, optionally substituted C3-C5 cycloalkylene, or optionally substituted 4- to 10-membered heterocyclylene;
• C is optionally substituted 3- to 10-membered cycloalkyl;
• optionally substituted 6- to 10-membered aryl;
• optionally substituted 5- to 10-membered heteroaryl;
• or optionally substituted 5- to 10-membered heterocyclyl;
• R1 and R7 are, independently, hydrogen or optionally substituted C1-C6 alkyl;
• each R2 and R3 is independently, hydrogen, optionally substituted C1-C6 alkyl;
• or
• optionally substituted C1-C6 heteroalkyl;
• R4 is cyano, fluoro, hydroxy, or —CH2OH;
• R5 is C1-C3 alkyl optionally substituted with one, two, three, four, five, six, or seven fluoro groups;
• and
• R6 is C1-C3 alkyl optionally substituted with one, two, three, four, five, six, or seven fluoro groups,
• or a pharmaceutically acceptable salt thereof.