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AssigneeVyome Therapeutics Limited
InventorsAshwani SINGH RAWAT, Charles CHAVDARIAN, Jitesh BEHERA, Mau SINHA, Mukesh KUMAR GARG, Shamik GHOSH, Shiladitya SENGUPTA, Sumana GHOSH
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The present invention relates to formulations and their use to treat ocular disorders such as uveitis. Particularly, the invention relates to a formulation comprising mycophenolic acid (MPA) or a pharmaceutically acceptable salt or derivative thereof; and at least one component selected from the group consisting of preservative, chelating agent, buffering agent, pH modifier, thickening agent, viscosity enhancer or viscosity modifier, antioxidant, tonicity modifier, surfactant, humectant, solvent or co-solvent, emulsifier, co-emulsifier, ointment base, targeting agent, polymer, wetting agent, lubricating agent, suspending agent, and therapeutic agent. The disclosure further provides preparation method of said ophthalmic formulations, a pharmaceutical kit comprising said formulations, and method for treating ocular diseases by administering said formulations. The present formulations are advantageous and can be delivered to the eye with increased retention time in the eye and increased bioavailability of mycophenolic acid, or a pharmaceutically acceptable salt or derivative thereof in the eye.
A formulation comprising:
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The method as claimed in claim 17, wherein:
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A Use of mycophenolic acid (MPA) or a pharmaceutically acceptable salt or derivative thereof for the treatment of Lichen sclerosus.
Dependencies are inferred from the claim text.