Stable ascorbic acid compositions and methods of using same
AssigneeRenovion, Inc.
InventorsDan COPELAND, Carolyn DURHAM
Life of this patent
Estimating the term…
Abstract
The application is directed a composition comprising organic acid (e.g., ascorbic acid), glutathione, a glutathione derivative, a glutathione conjugate, a pharmaceutically-acceptable salt thereof, or any combination thereof, and methods of using the same. In certain aspects the application is directed to glutathione, a glutathione derivative, a glutathione conjugate, a pharmaceutically-acceptable salt thereof; and an organic acid; wherein the molar ratio is about 0.5-1:1. The composition can further comprises a bicarbonate salt, wherein the molar ratio is about 0.1-0.5:0.5-1:1.
Claims24
1-94. (canceled)
A method of treating a subject having a pulmonary or airway viral infection, comprising administering to the subject a therapeutically effective amount of a composition comprising:
- (a) glutathione, a glutathione derivative, a glutathione conjugate, or a pharmaceutically-acceptable salt thereof;
- (b) an ascorbic acid;
- and
- (c) a bicarbonate,
- wherein the molar ratio of (a):(b):(c) is about 0.1-0.5:0.5-1:1.
A method of upregulating mucociliary clearance in a subject suffering from a pulmonary or airway viral infection comprising administering to the subject a composition comprising:
- (a) glutathione, a glutathione derivative, a glutathione conjugate, or a pharmaceutically-acceptable salt thereof;
- (b) an ascorbic acid;
- and
- (c) a bicarbonate, wherein the molar ratio of (a):(b):(c) is about 0.1-0.5:0.5-1:1.
Dependencies are inferred from the claim text.