Cell-penetrating peptide and use thereof
AssigneeImnewrun, Inc.
InventorsHan Joo KIM, Minah SUH, Yong Ho KIM, Jae Cheol LEE, Euna LEE, Ji Young NAM, Ho Jae CHOI
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Abstract
The present disclosure relates to novel cell penetrating peptides and uses thereof. Since 12 types of cell-penetrating peptides according to the present disclosure were confirmed to have excellent cell permeability and an excellent substance delivery effect in vitro and in vivo, the cell-penetrating peptides are expected to be useful in the field of research, and in the field of diagnosis or treatment of various diseases, by being capable of effectively delivering a substance with biological activity into the body, such as cells and tissues.
Claims14
A cell-penetrating peptide consisting of amino acids represented by General Formula 1 below:
- X1-X2- . . . Xn-1-Xn, General Formula 1
- wherein in General Formula 1, n ≥16, X2 is His (H), X6 is Leu (L), and amino acids other than X2 and X6 are any one selected from the group consisting of Gly (G), His (H), Glu (E), Arg (R), Lys (K), Ser (S), Asp (D), Trp (W), Val (V), Thr (T), Ala (A), Asn (N) and Tyr (Y).
Dependencies are inferred from the claim text.