US 2023/0144344 A1 · COMPOSITION FOR PREVENTING OR TREATING CARDIOVASCULAR AND METABOLIC DISEASES COMPRISING ELAEOCARPUS PETIOLATUS

Composition for preventing or treating cardiovascular and metabolic diseases comprising elaeocarpus petiolatus

AssigneesSeoul National University Hospital, Korea Research Institute of Bioscience and Biotechnology

InventorsHyo-soo KIM, Hyun-duk JANG, Kyung Seop AHN, Sei-Ryang OH, Ok-Kyoung KWON, Hyung Won RYU, Hang JIN, Sangho CHOI, Sang Woo LEE, Jin Hyub PAIK, Soo Yong KIM, Changyoung LEE, Yong In KIM, Hyewon KIM, Mijin PARK

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Abstract

The present invention relates to a pharmaceutical composition for preventing or treating cardiovascular and metabolic diseases, comprising an Elaeocarpus petiolatus extract, a fraction thereof, or a compound isolated therefrom, as an active ingredient; a food composition for preventing or improving cardiovascular and metabolic diseases; and a method for preventing or treating cardiovascular and metabolic diseases using the same. The composition comprising an Elaeocarpus petiolatus extract, a fraction thereof, or a compound isolated therefrom inhibits the binding of Resistin-CAP1 to inhibit the production of tumor necrosis factor, and thereby has an activity of inhibiting inflammation of the cardiovascular system, and thus can be effectively used as a preventive or therapeutic measure for cardiovascular and metabolic diseases.

Claims12

Dependent claims

A method for treating cardiovascular and metabolic diseases, comprising:

administering a composition comprising an Elaeocarpus petiolatus extract, a fraction thereof, or a compound isolated therefrom, as an active ingredient to the subject in need thereof.

Dependencies are inferred from the claim text.