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US 2023/0144152 A1Published application
Boronic acid derivatives and therapeutic uses thereof
AssigneeQpex Biopharma, Inc.
InventorOlga Lomovskaya
Life of this patent
Estimating the term…
Abstract
Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the method of use and preparation thereof. Some embodiments relate to boronic acid derivatives and their use as therapeutic agents, for example, β-lactamase inhibitors (BLIs).
Claims23
A pharmaceutical composition comprising a therapeutically effective amount of a compound having the structure:
- or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient;
- and further comprising an additional medicament, wherein the additional medicament is cefiderocol, ceftolozane or sulbactam.
(canceled)
A method of treating a bacterial infection, comprising administering to a subject in need thereof a compound having the structure:
- or a pharmaceutically acceptable salt thereof, and an additional medicament, wherein the additional medicament is cefiderocol, ceftolozane or sulbactam.
(canceled)
(canceled)
Dependencies are inferred from the claim text.