Immune effector cell in which expression is regulated by cytokines
AssigneeCrage Medical Co., Limited
InventorsZonghai LI, Hua JIANG
Life of this patent
Estimating the term…
Abstract
Provided is a genetically engineered immune effector cell, wherein the immune effector cell expresses a receptor specifically recognizing a target antigen and IL7, and the IL-7 is inducibly expressed and regulated by the receptor. Further provided are a nucleic acid molecule expressing the receptor and IL7 in the immune effector cell and a method for preparing the immune effector cell.
Claims22
1-40. (canceled)
A genetically engineered immune effector cell, characterized in that the immune effector cell expresses a receptor specifically recognizing a target antigen and IL7, and the IL-7 is inducibly expressed and regulated by the receptor.
Dependencies are inferred from the claim text.