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US 2023/0143752 A1Published application
Cannabidiol nanodrug formulations and methods for use of the same
AssigneeUniversity of Miami
InventorsNadia Peyravian, Sylvia Daunert, Joaquin J. Jimenez, Suzana Hamdan, Naiem Issa, Sapna K. Deo, Assuan Lens
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Abstract
Disclosed herein are topical formulations of cannabidiol, such as nanoparticulate cannabidiol, methods of making such compositions, and their use in treating autoimmune diseases and disorders, e.g., alopecia areata.
Claims59
A topical composition comprising:
- (a) nanoparticulate cannabidiol having an average particle size of about 5 nm to about 1000 nm;
- and
- (b) a pharmaceutically acceptable carrier,
- wherein the nanoparticulate cannabidiol is capable of penetrating into the skin.
1 more element
A topical composition comprising:
- (a) cannabidiol;
- (b) minoxidil;
- and
- (c) a pharmaceutically acceptable carrier comprising ethanol, propylene glycol, and water,
- wherein the cannabidiol is capable of penetrating into the skin.
2 more elements
A topical composition comprising about 0.01% to about 15% by weight cannabidiol and about 1% to about 15% by weight minoxidil.
A method of preparing nanoparticulate cannabidiol comprising the steps of:
- (a) dissolving cannabidiol in a solvent to form a first solution;
- (b) admixing the first solution with an antisolvent that is miscible with the solvent to form a second solution;
- and
- (c) mixing the second solution at a rate in a range of about 300 to about to 5,000 rpm.
1 more element
Dependencies are inferred from the claim text.