Determining Effectiveness of Sterilization Procedure from Outside the Sterilization Package

A sterilization indicator, comprising:

• a cover defining at least a portion of a cavity;
• an indicator disposed within the cavity, wherein the indicator is configured to fluidly couple with an internal cavity of a sterilization package and indicate an exposure to a sterilant;
• and
• a seal configured to form a microorganism barrier between an exterior of the cover and the cavity of the sterilization package;
• wherein the sterilization indicator defines a laminate structure, wherein the cover comprises a cover layer, and wherein the indicator comprises an indicator layer disposed on the cover layer;
• further comprising a base, wherein the indicator layer is dimensionally smaller than the base, and edges of the base extend beyond the indicator, and wherein at least a portion of the edges of the base are coupled to at least a portion of the edges of the cover;
• wherein the base defines a second surface opposing the cover, and wherein at least a portion of the second surface of the base is configured to couple with an exterior of the sterilization package.