Estimation of Admixture Generation

A non-transitory computer-readable medium storing program instructions that, when executed by one or more processors of a computing system, cause the computing system to perform operations comprising:

• comparing representations of a plurality of genetic segments of an individual to a plurality of reference ancestry models, wherein the reference ancestry models are stored in a database and are respectively associated with different ancestries;
• determining, based on the comparison, that one or more genetic segments of the plurality of genetic segments correspond to a specific ancestry;
• determining, for the individual, genetic ancestry summary data corresponding to the specific ancestry, wherein the genetic ancestry summary data includes at least one of:
• a number of the one or more genetic segments that correspond to the specific ancestry, a number of chromosomes carrying the one or more genetic segments that correspond to the specific ancestry, or lengths of each of the one or more genetic segments that correspond to the specific ancestry;
• applying maximum likelihood estimation to the genetic ancestry summary data as fit to a genetic recombination model, the genetic recombination model associating respective genetic characteristics to predicted numbers of generations between a subject having genetic characteristics and at least one non-admixed ancestor of the specific ancestry;
• determining, from the maximum likelihood estimation, one or more estimated numbers of generations between the individual and a non-admixed ancestor of the individual, the non-admixed ancestor having the specific ancestry;
• and
• providing, for graphical display on a user interface, the one or more estimated numbers of generations and the specific ancestry.

A computing system comprising:

• a processor;
• memory;
• and
• program instructions, stored in the memory, that upon execution by the processor cause the computing system to perform operations comprising:
• comparing representations of a plurality of genetic segments of an individual to a plurality of reference ancestry models, wherein the reference ancestry models are stored in a database and are respectively associated with different ancestries;
• determining, based on the comparison, that one or more genetic segments of the plurality of genetic segments correspond to a specific ancestry;
• determining, for the individual, genetic ancestry summary data corresponding to the specific ancestry, wherein the genetic ancestry summary data includes at least one of:
• a number of the one or more genetic segments that correspond to the specific ancestry, a number of chromosomes carrying the one or more genetic segments that correspond to the specific ancestry, or lengths of each of the one or more genetic segments that correspond to the specific ancestry;
• applying maximum likelihood estimation to the genetic ancestry summary data as fit to a genetic recombination model, the genetic recombination model associating respective genetic characteristics to predicted numbers of generations between a subject having genetic characteristics and at least one non-admixed ancestor of the specific ancestry;
• determining, from the maximum likelihood estimation, one or more estimated numbers of generations between the individual and a non-admixed ancestor of the individual, the non-admixed ancestor having the specific ancestry;
• and
• providing, for graphical display on a user interface, the one or more estimated numbers of generations and the specific ancestry.