Polypeptide monolayer with low potential and hydrophobicity, and preparation method and application
AssigneeQilu University of Technology
InventorsTianduo LI, Jing XU, Qing BAN, Huijun MA, Zhen ZHANG
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AssigneeQilu University of Technology
InventorsTianduo LI, Jing XU, Qing BAN, Huijun MA, Zhen ZHANG
Estimating the term…
A polypeptide monolayer with a low surface potential and hydrophobicity. The polypeptide is composed of polypeptide molecules with a molecular weight of (1.48±0.2)×105 g/mol, a thickness of the monolayer is 6.2-9.0 nm, the exposure of primary amino groups on the surface of the monolayer is 9.5-15%, a Zeta potential of the polypeptide monolayer is (−3)−(−9) mV, and a contact angle of the monolayer is (61±1°)-(84±1°). The monolayer can be ultrathin, with a minimum thickness of only about 6.6 nm. The polypeptide monolayer can also be applied to the preparation of a biosensor, which is conductive to increase in limit of detection. The content of primary amino groups on the surface of polypeptide monolayer is conductive to controllability of further chemical modification and laying the foundation for achieving controllable grafting of polysiloxane and biological preparations in the later stage.
A polypeptide monolayer with a low surface potential and hydrophobicity, characterized in that the polypeptide is composed of polypeptide molecules with a molecular weight of (1.48±0.2)×105 g/mol, a thickness of the monolayer is 6.2-9.0 nm, the exposure of primary amino groups on the surface of the monolayer is 9.5-15%, a Zeta potential of the polypeptide monolayer is (−3)-(−9) mV, and a contact angle of the monolayer is (61±1°)-(84±1°).
A composite film containing a polypeptide monolayer, characterized by comprising a polyethyleneimine thin film and a polypeptide monolayer, wherein the polyethyleneimine thin film and the polypeptide monolayer are bound together via ionic bonds, a thickness of the polyethyleneimine thin film is 0.25-0.38 nm, and a thickness of the polypeptide monolayer is 6.2-9.0 nm.
Dependencies are inferred from the claim text.