Polypeptide monolayer with high potential and hydrophobicity, and preparation method and application thereof
AssigneeQilu University of Technology
InventorsJing XU, Qing BAN, Tianduo LI, Zhen ZHANG, Huijun MA
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AssigneeQilu University of Technology
InventorsJing XU, Qing BAN, Tianduo LI, Zhen ZHANG, Huijun MA
Estimating the term…
A polypeptide monolayer with a high surface potential and hydrophobicity, and a preparation method and application thereof. The polypeptide is composed of polypeptide molecules with a molecular weight of (1.48±0.2)×105 g/mol, a thickness of the monolayer is 17.3-18.5 nm, the exposure of primary amino groups on the surface of the monolayer is 11-11.8%, a Zeta potential of the polypeptide monolayer is (-3)-(-2) mV, and a contact angle of the monolayer is 84±1°. A micro-nano structure on the surface of the polypeptide monolayer allows the polypeptide monolayer to have certain hydrophobicity, which is beneficial to water proofing of the surface of biomimetic skin. Furthermore, the surface of the polypeptide monolayer has a relatively high potential, which can improve biocompatibility, hemocompatibility, and cell adhesion, proliferation, and differentiation abilities.
A polypeptide monolayer with a high surface potential and hydrophobicity, characterized in that the polypeptide is composed of polypeptide molecules with a molecular weight of (1.48±0.2)x105 g/mol, a thickness of the monolayer is 17.3-18.5 nm, the exposure of primary amino groups on the surface of the monolayer is 11-11.8%, a Zeta potential of the polypeptide monolayer is (-3)-(-2) mV;
A composite film containing a polypeptide monolayer, characterized by comprising a polyethyleneimine thin film and a polypeptide monolayer, wherein the polyethyleneimine thin film and the polypeptide monolayer are bound together via ionic bonds, a thickness of the polyethyleneimine thin film is 0.25-0.38 nm, and a thickness of the polypeptide monolayer is 17.3-18.5 nm.
Dependencies are inferred from the claim text.