Compounds for treating or preventing a coronaviridae infection & methods and uses for assessing the occurrence of a coronaviridae infection
AssigneeAbivax
InventorsJamal TAZI, Hartmut EHRLICH, Philippe POULETTY, Julien SANTO, Didier SCHERRER
Life of this patent
Estimating the term…
Abstract
The treatment or prevention of a Coronaviridae infection, and conditions related thereto; in particular a Coronaviridae infection in humans. In particular, the compounds, pharmaceutical compositions and medicaments for treating and/or preventing a Coronaviridae infection and/or its long-term consequences. The uses and methods for assessing a Coronaviridae infection or the efficacy of a treatment of such infections.
Claims22
-22. (canceled)
A method for treating or preventing a Coronaviridae infection and conditions related thereto, comprising administering a compound of formula (I)
- or any one of its prodrugs or any one of its pharmaceutically acceptable salts.
A method for treating or preventing a Coronaviridae infection and conditions related thereto, comprising administering a compound of formula (II)
- or any one of its prodrugs or any one of its pharmaceutically acceptable salts.
An in vitro or ex vivo method for determining the efficacy of a therapeutic treatment of a Coronaviridae infection and conditions related thereto, comprising measuring a presence or level of expression of at least one miRNA, said at least one miRNA being miR-124.
An in vitro or ex vivo method for assessing a Coronaviridae infection in a patient presumed to be infected with a virus, comprising at least the steps of:
- a—measuring a presence or an expression level of at least one miRNA, said at least one miRNA being miR-124, in a biological sample previously obtained from said patient;
- and
- b—comparing said presence or expression level to a control reference value, wherein a modulated presence or level of expression of said miRNA relative to said control reference value is indicative of a Coronaviridae infection.
Dependencies are inferred from the claim text.