Treatment of infectious diseases
AssigneesDurect Corporation, Virginia Commonwealth University
InventorsSHUNLIN REN, WEIQI LIN, JAMES E. BROWN
Life of this patent
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Abstract
Methods of treating infectious diseases are provided. For instance, the methods may comprise administering at least one antimicrobial in combination with at least one oxygenated cholesterol sulfate (OCS). Methods for preventing and/or treating organ dysfunction and/or organ failure for patients with an infectious disease are described herein. Methods for preventing and/or treating tissue damage of one or more organs or organ systems for patients with an infectious disease are described herein.
Claims20
A method of treating an infectious disease in a human subject in need thereof, the method comprising administering to the subject at least one antimicrobial and at least one oxygenated cholesterol sulfate (OCS) in an amount that is sufficient to treat the infectious disease.
A method of preventing or treating dysfunction or failure of one or more organs or organ systems in a human subject in need thereof and suffering from an infectious disease, comprising:
- administering to the subject an amount of at least one oxygenated cholesterol sulfate (OCS) that is sufficient to prevent or treat the dysfunction or failure of the organ or organ system.
A method of preventing or treating tissue damage of one or more organs or organ systems in a human subject in need thereof and suffering from an infectious disease, comprising:
- administering to the subject an amount of at least one oxygenated cholesterol sulfate (OCS) that is sufficient to prevent or treat tissue damage of the organ or organ system.
A method of treating an infectious disease in a human subject in need thereof, the method comprising administering to the subject at least one oxygenated cholesterol sulfate (OCS) in an amount that is sufficient to treat the infectious disease.
A method comprising administering to a subject diagnosed with COVID-19 a therapeutically effective amount of remdesivir and 25HC3S or a salt thereof.
Use of remdesivir and 25HC3S or a salt thereof in the treatment of COVID-19
A composition comprising remdesivir and 25HC3S or a salt thereof for use in the treatment of COVID-19.
Use of remdesivir and 25HC3S or a salt thereof in the manufacture of a medicament for use in a method of treating COVID-19.
Dependencies are inferred from the claim text.