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AssigneesInternational Business Machines Corporation, Agency for Science, Technology and Research
InventorsJames L. Hedrick, Yi Yan Yang, Agnes Mari Kuroki, Jiayu Eunice Leong, Wei Ping Eddy Tan
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A water-soluble polymer having an aliphatic polycarbonate backbone, a first carbonate monomer with at least one hydrophilic functionality, and a second carbonate monomer with at least one hydrophobic functionality is able to completely and quickly eliminate a virus from a human and/or animal cell. The at least one hydrophilic functionality is a sulfate, a sulfonate, a carboxylate, and/or a phosphate and the at least one hydrophobic functionality is an alkyl. The hydrophilic/hydrophobic functionalities of the polymer may be tuned to enhance the antiviral properties of the polymer and/or to decrease any cytotoxicity associated with the application of the polymer to a human and/or animal cell. The antiviral polymer is biocompatible and biodegradable.
A composition comprising a water-soluble polymer with an aliphatic polycarbonate backbone, a first carbonate monomer with at least one hydrophilic functionality;
The composition of claim 6, wherein the anti-viral potency of the water-soluble polymer is tunable by altering the concentrations of the at least one hydrophilic functionality and the at least one hydrophobic functionality.
A composition comprising a water-soluble polymer with an aliphatic polycarbonate backbone, at least one carbonate monomer with a hydrophilic sulfonate group, and at least one carbonate monomer with a hydrophobic alkyl group.
A method for inhibiting viral infections in a human or animal subject comprising:
Dependencies are inferred from the claim text.