Genetically modified clostridium bacteria, preparation and uses of same
AssigneeIfp Energies Nouvelles
InventorsRÈMI HOCQ, GWLADYS CHARTIER, FRANÇOIS WASELS, NICOLAS LOPES FERREIRA
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Abstract
The present invention relates to the genetic modification of bacteria of the genus Clostridium, typically solventogenic bacteria of the genus Clostridium, in particular bacteria possessing in the wild type a gene encoding an amphenicol-O-acetyltransferase. It thus relates to methods, tools and kits allowing such a genetic modification, in particular the removal or modification of a sequence encoding or controlling the transcription of an amphenicol-O-acetyltransferase, to the genetically modified bacteria obtained and to uses thereof, in particular for producing a solvent, preferably on an industrial scale.
Claims18
1-15. (canceled)
A nucleic acid recognizing the catB gene of sequence SEQ ID NO:
- 18 or a sequence at least 70% identical thereto within the genome of a bacterium of the genus Clostridium.
A C. beijerinckii DSM6423 ΔcatB bacterium deposited under the number LMG P-31151.
Dependencies are inferred from the claim text.