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US 2023/0108258 A1Published application
Antibody-free rapid detection of sars-cov-2 proteins using corona phase molecular recognition (cophmore)
AssigneeMassachusetts Institute of Technology
InventorsSooyeon Cho, Michael Strano, Xiaojia Jin, Xun Gong, Sungyun Yang, Jianqiao Cui
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Abstract
Corona phase molecular recognition (CoPhMoRe) that enables the molecular recognition of SARS-CoV-2 viral proteins without the need for antibody or enzymatic receptor incorporation.
Claims23
A sensor comprising a nanoparticle structure including a lipid functionalized polyethylene glycol associated with a carbon nanotube.
A method of developing a sensor for a virus comprising:
- selecting a polymer screening array based on one or more structural features of the virus;
- assembling a plurality of test sensors by associating each member of the polymer screening array with a carbon nanotube;
- assessing a response of each of the plurality of test sensors to the one or more structural features of the virus;
- and
- selecting the sensor based on the response.
2 more elements
Dependencies are inferred from the claim text.