Cycloalkyl-containing carboxylic acids and uses thereof

A compound of formula (I) or a salt thereof:

• wherein:
• A represents a 3- to 6-membered cycloalkane or heterocycloalkane, wherein the cycloalkane or heterocycloalkane are optionally bridged,
• R1 represents a covalent bond or an alkylene or alkenylene chain, wherein the alkylene or alkenylene chain is optionally substituted with ═O,
• R2 represents a hydrogen atom or an alkyl or alkenyl chain, wherein:
• the alkyl or alkenyl chain is optionally substituted with a hydroxy group, or
• the alkyl or alkenyl chain is optionally terminated with a carboxyl group or with a 3- to 6-membered cycloalkyl, heterocycloalkyl, aryl or heteroaryl, and
• the cycloalkyl, heterocycloalkyl, aryl, and heteroaryl are optimally substituted with one or more alkyl groups, and
• R3 and R4 are identical to each other or different, are both attached to a same ring atom of A, and represent hydrogen atoms, deuterium atoms, halogen atoms, or methyl groups, or
• R3 represents R2, wherein R2 is as defined above, and R4 represents a hydrogen atom,
• R1 and R2 are attached on a same ring atom of A or on different ring atoms of A,
• wherein the atom of R1, or of A if R1 is a covalent bond, that bears the —COOH group is optionally substituted with a second —COOH group,
• wherein A, R1 and R2 are such that the shortest continuous chain of carbon atoms and, if present, heteroatoms linking:
• the carbon atom or ring heteroatom in R2 that is farthest from R1 or, if R2 represents a hydrogen atom, the ring carbon atom or ring heteroatom in A that is farthest from R1;
• to the carbon atom of the COOH group terminating R1
• is 9 to 11 atoms long,
• wherein the COOH group may be replaced by an isostere thereof;
• and wherein the compound is not
• (cascarillic acid) or
• (cis-2-(2-hexylcyclopropyl)-acetic acid).