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US 2023/0106760 A1Published application
Antibacterial and antifungal polyketides from environmental amycolatopsis spp
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsCarole A. Bewley Clore, Hongbing Liu, Shannon I. Ohlemacher
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Abstract
Disclosed are compounds represented by the formula:(I), wherein R is as defined herein, and pharmaceutically acceptable salts thereof. Also disclosed are a method of treating a subject in need of treatment for a bacterial infection or a fungal infection, which includes administering to the subject an effective amount of one of the compounds or salts thereof. Further disclosed is a process for producing the compounds and salts thereof.
Claims20
A compound represented by the structure:
- wherein R is selected from
- or a pharmaceutically acceptable salt thereof.
7-12. (canceled)
Dependencies are inferred from the claim text.