Catalytic cannabigerol processes and precursors
AssigneeKare Chemical Technologies Inc.
InventorsKamaluddin ABDUR-RASHID, Wenli JIA, Kareem ABDUR-RASHID
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to cannabigerol sulfonate esters and processes for their use to prepare cannabigerol (CBG) and related compounds, including cannabigerobutol (CBGB), cannabigerovarin (CBGV), and cannabigerophorbol (CBGP). In a preferred embodiment, the cannabigerol sulfonate ester is (E)-4-(3, 7-5 dimethylocta-2,6-dienyl)-3,5-bis(trimethylsilyloxy)phenylromethanesulfonate. In a preferred process, the trifluoromethansulfonate leaving group is replaced by an alkyl group. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabigerol and related compounds from the cannabigerol sulfonate esters.
Claims28
A compound of Formula (I):
- wherein, R1 represents a hydrogen atom, a linear or branched alkyl group of any length, possibly substituted, or an alkenyl group of any length, possibly substituted, or an alkynyl group, possibly substituted, or a cycloalkyl group, possibly substituted, or an aryl group, possibly substituted, or an heteroaryl group, possibly substituted, or an ORc group or an NRc2 group, possibly substituted, with possible and non-limiting substituents of R1 being halogen atoms, ORc, or NRc2 groups, in which Rc is a hydrogen atom or a cyclic, linear or branched alkyl, aryl or alkenyl group, and all stereoisomers thereof.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
-28. (canceled)
A compound of the Formula (A):
- wherein LG is a suitable leaving group.
Dependencies are inferred from the claim text.