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AssigneesAnhui Huaheng Biotechnology Co., Ltd., Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
InventorsXueli ZHANG, Henghua GUO, Pingping LIU, Dongzhu ZHANG, Jinlei TANG, Chengxiu HAN, Siqing TANG, Shupeng LIU, Yanhe MA
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Related are a recombinant microorganism for producing L-valine, a construction method and an application thereof. Through transferring an amino acid dehydrogenase gene and/or activating activity of a transhydrogenase and/or a NAD kinase, reducing power of NADPH in cell is increased, the titer and yield of L-valine generated by Escherichia coli are improved, and the production of L-valine by one-step anaerobic fermentation is achieved.
A construction method of a recombinant microorganism for producing L-valine, comprising:
A recombinant microorganism, wherein a preservation number thereof is CGMCC 19456.
(canceled)
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