Process and system for acellular therapy
AssigneeOrgenesis Inc.
InventorSabina GLOZMAN
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Abstract
Process and system for acellular therapy in a human subject are provided. The process and system relate to an acellular therapy using therapeutic extracellular vehicles fused to biological material obtained from the subject, via transfusion by extracorporeal systems. The process for acellular therapy is in a subject in need of such therapy.
Claims32
A process for acellular therapy in a subject in need of such therapy, the process comprising:
- a) obtaining a biological material from the subject;
- b) optionally, eliminating vesicle content from the biological material;
- c) providing a sample of essentially purified therapeutic extracellular vesicles;
- d) fusing the therapeutic extracellular vesicles of step c with the biological material of step a to obtain a biological material comprising therapeutic extracellular vesicles;
- and, e) transfusing the biological material of step d to the subject, wherein the transfusion is extracorporeal transfusion.
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A system for acellular therapy comprising a)a fusion unit comprising a housing and, optionally, movement-inducing element, said fusion unit is configured to promote fusion of therapeutic extracellular vesicles with a biological material obtained from a human subject to thereby obtain a biological sample comprising said therapeutic extracellular vesicles;
- b) therapeutic extracellular vesicles supply unit configured to supply a sample of therapeutic extracellular vesicles to the fusion unit;
- and c)a transfusion unit configured to transfuse the biological material comprising the therapeutic extracellular vesicles to the human subject.
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Dependencies are inferred from the claim text.