# US 2023/0067979 A1 · An ingestible therapeutic device for the treatment of gastritis

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- Number: US 2023/0067979 A1
- Document ID: US20230067979A1
- Status: Published application
- Kind: A1
- Application number: 17/759,780
- Filed: 2021-02-01
- Published: 2023-03-02
- Earliest claimed: 2020-01-31
- Assignees: Cosmoaesthetics Pty Ltd
- Applicants: Cosmoaesthetics Pty Ltd
- Inventors: Masoud Tahghighi JAFARZADEH
- Web page: https://patentgrep.com/patent/US20230067979A1

## CPC

- A61N 5/0601: {Apparatus for use inside the body}
- A61N 5/0603: {for treatment of body cavities}
- A61N 5/0613: {Apparatus adapted for a specific treatment}
- H01G 11/08: Structural combinations, e.g. assembly or connection, of hybrid or EDL capacitors with other electric components, at least one hybrid or EDL capacitor being the main component
- A61N 2005/0609: {Stomach and/or esophagus}
- A61N 2005/0626: {Monitoring, verifying, controlling systems and methods}
- A61N 2005/0632: {Constructional aspects of the apparatus}
- A61N 2005/0651: {Diodes}
- A61N 2005/0659: {infrared}
- A61N 2005/0662: {Visible light}
- A61N 2005/0663: {Coloured light}
- H01G 11/06: with one of the electrodes allowing ions to be reversibly doped thereinto, e.g. lithium ion capacitors [LIC]
- H01G 11/50: specially adapted for lithium-ion capacitors, e.g. for lithium-doping or for intercalation
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- H01G: CAPACITORS; CAPACITORS, RECTIFIERS, DETECTORS, SWITCHING DEVICES, LIGHT-SENSITIVE OR TEMPERATURE-SENSITIVE DEVICES OF THE ELECTROLYTIC TYPE (selection of specified materials as dielectric H01B3/00; capacitors having potential barriers H10D1/62, H10K10/10)

## Abstract

An ingestible gastrointestinal phototherapy device has a spherocylindrical body of non-digestible material having a cylindrical midsection and transparent light portals at ends thereof. The cylindrical midsection has control circuitry and a power source therein and each light portal is transparent and comprises an array of bioactive light source elements therein emitting bioactive light therefrom and being operably coupled to the control circuitry and power source.

## Claims

### Claim 1

An ingestible gastrointestinal phototherapy device comprising a spherocylindrical body of non-digestible material having a cylindrical midsection and transparent light portals at ends thereof, the cylindrical midsection comprising control circuitry and a power source therein and wherein each light portal is transparent and comprises an array of bioactive light source elements therein emitting bioactive light therefrom and being operably coupled to the control circuitry and power source and wherein the light source elements comprise an axial light source element orientated along a longitudinal axis of the spherocylindrical body and a plurality of radial light source elements around the axial light source element, each radial light source element orientated substantially orthogonally with respect to the longitudinal axis, having a cast angle of greater than 100° along the longitudinal axis and located within a respective portal such that light cast by radial light source elements from opposite ends of the body coincides at a midpoint having a perpendicular distance from the side of the cylindrical midsection being less than half and the distance between the longitudinally aligned radial light source elements.

### Claim 2 (depends on 1)

The device as claimed in claim 1, wherein each radial light source element is located beyond a base of the respective portal.

### Claim 3 (depends on 2)

The device as claimed in claim 2, wherein each radial light source element is located on a respective outer surface of a plinth extending from the base of the respective portal.

### Claim 4 (depends on 3)

The device as claimed in claim 3, wherein each light portal comprises a distal hemispherical section and a proximal cylindrical section adjacent the midsection.

### Claim 5 (depends on 1)

The device as claimed in claim 1, wherein each radial light source element has a cast angle of approximately 120° along the longitudinal axis.

### Claim 6 (depends on 1)

The device as claimed in claim 1, wherein each radial light source element has a cast angle in a plane orthogonal respect to the longitudinal axis of greater than 100°.

### Claim 7 (depends on 6)

The device as claimed in claim 6, wherein each radial light source element has a cast angle in a plane orthogonal respect to the longitudinal axis of approximately 120°.

### Claim 8 (depends on 1)

The device as claimed in claim 1, wherein the control circuitry is preprogrammed with a plurality of operational modes and wherein control circuitry operates the light source elements accordingly.

### Claim 9 (depends on 8)

The device as claimed in claim 8, wherein, when selecting an operational mode of operation, the control circuitry operates the light source elements to indicate the selection of the operational mode.

### Claim 10 (depends on 8)

The device as claimed in claim 8, wherein the light source elements comprise first and second sets emitting light at different wavelength ranges.

### Claim 11 (depends on 10)

The device as claimed in claim 10, wherein the control circuitry operates either set depending on a selected operational mode.

### Claim 12 (depends on 1)

The device as claimed in claim 1, wherein the midsection is flexible and wherein the control circuitry comprises a pressure switch adjacent the midsection to detect pressure applied to the midsection.

### Claim 13 (depends on 12)

The device as claimed in claim 12, wherein the control circuitry comprises at least two pressure switches located oppositely with respect to the longitudinal axis.

### Claim 14 (depends on 1)

The device as claimed in claim 1, wherein the control circuitry comprises a wireless transceiver.

### Claim 15 (depends on 14)

The device as claimed in claim 14, wherein the wireless transceiver comprises an antenna responsive to a radio frequency such that the control circuitry selects a mode of operation when exposed to the frequency.

### Claim 16 (depends on 14)

The device as claimed in claim 14, wherein the wireless transceiver is a wireless data transceiver.

### Claim 17 (depends on 10)

The device as claimed in claim 10, wherein the first set emits light in the wavelength range of 660 and 680 nm.

### Claim 18 (depends on 10)

The device as claimed in claim 10, wherein the first set emits light in the wavelength range of 510-810 nm.

### Claim 19 (depends on 1)

The device as claimed in claim 1, wherein the light portal comprises at least one lens.

### Claim 20 (depends on 19)

The device as claimed in claim 19, wherein the at least one lens comprises a plurality of adjacent lenses.

### Claim 21 (depends on 20)

The device as claimed in claim 20, wherein the plurality of adjacent lenses are hexagonal.

### Claim 22 (depends on 1)

The device as claimed in claim 1, wherein the control circuitry comprises a sensor and wherein the control circuitry is configured to detect a peristaltic wave characteristics in the at least one sensor and to infer a location within a gastrointestinal tract according to the peristaltic wave characteristic and wherein the control circuitry controls the at least one light source element according to the location.

### Claim 23 (depends on 22)

The device as claimed in claim 22, wherein the control circuitry differentiates between the large and small intestines according to a frequency peristaltic wave characteristic.

### Claim 24 (depends on 22)

The device as claimed in claim 22, wherein the sensor comprises an accelerometer which detects acceleration of the body when a peristaltic wave occurs within the gastrointestinal tract.

### Claim 25 (depends on 22)

The device as claimed in claim 22, wherein the sensor comprises a pressure sensor which detects pressure changes to the body when a peristaltic wave occurs within the gastrointestinal tract.

### Claim 26 (depends on 22)

The device as claimed in claim 22, wherein the sensor comprises an audio sensor which detects audio frequencies generated when a peristaltic wave occurs within the gastrointestinal tract.

### Claim 27 (depends on 22)

The device as claimed in claim 22, wherein the control circuitry controls at least one light source element according to the location by operating the at least one light source element at a first location and not operating the at least one light source element at a second location.

### Claim 28 (depends on 22)

The device as claimed in claim 22, wherein the light source elements comprise first and second sets emitting light at different wavelength ranges and wherein the control circuitry controls the light source elements to emit light at different wavelength ranges depending on the location.

### Claim 29 (depends on 1)

The device as claimed in claim 1, wherein the light source elements comprise first and second sets emitting light of different wavelength ranges and wherein the control circuitry comprises an orientation sensor which determines an orientation of ingestion and wherein the control circuitry controls the first and second sets to emit light frequency forward of the body at a different frequency as to rearward of the body.

### Claim 30 (depends on 1)

The device as claimed in claim 1, wherein the device comprises a deployable anchor mechanism comprises at least one extendable anchor leg.

### Claim 31 (depends on 30)

The device as claimed in claim 30, wherein the anchor leg extends via a port through the body.

### Claim 32 (depends on 31)

The device as claimed in claim 31, wherein the anchor leg is flexible.

### Claim 33 (depends on 32)

The device as claimed in claim 32, wherein the anchor leg comprises inherent curvature.

### Claim 34 (depends on 33)

The device as claimed in claim 33, wherein the anchor leg is located at an end of the body and wherein the anchor leg curves towards the opposite end.

### Claim 35 (depends on 31)

The device as claimed in claim 31, wherein a proximal end of the anchor leg comprises a magnetically attractable lug located within a barrel comprising first and second annular electromagnets each of which can be controlled by the control circuitry to extend and retract the anchor leg.

### Claim 36 (depends on 30)

The device as claimed in claim 30, wherein the control circuitry comprises a timer and wherein the control circuitry is configured to extend the anchor leg after a first period.

### Claim 37 (depends on 36)

The device as claimed in claim 36, wherein the control circuitry is further configured for attracting the anchor leg after a second period after the first period.

### Claim 38 (depends on 30)

The device as claimed in claim 30, wherein the control circuitry comprises a wireless transceiver and wherein the control circuitry is configured to extend or retract the anchor leg according to wireless signals received via the wireless transceiver.

### Claim 39 (depends on 30)

The device as claimed in claim 30, wherein the control circuitry comprises a sensor and wherein the control circuitry is configured to detect a peristaltic wave characteristics in the at least one sensor and to infer a location within a gastrointestinal tract according to the peristaltic wave characteristic and wherein the control circuitry extends or retract the anchor leg according to the location.

### Claim 40 (depends on 1)

The device as claimed in claim 1, wherein the power supply comprises a supercapacitor.

### Claim 41 (depends on 40)

The device as claimed in claim 40, wherein the supercapacitor has a specific energy of greater than 4 Wh/kg.

### Claim 42 (depends on 41)

The device as claimed in claim 41, wherein the device is configured to power the LEDs for more than three hours.

### Claim 43 (depends on 42)

The device as claimed in claim 42, wherein the self-discharge time of the supercapacitor at room temperature is greater than one week.

### Claim 44 (depends on 1)

The device as claimed in claim 1, wherein the device as attached to a thread.

### Claim 45 (depends on 44)

The device as claimed in claim 44, wherein the device comprises a connection to which the thread is attachable.

### Claim 46 (depends on 45)

The device as claimed in claim 45, wherein one of the light portal comprises the connection and wherein the connection is a slotted recess into which a conforming engagement piece attached to the threaded engaged.

### Claim 47 (depends on 46)

The device as claimed in claim 46, wherein both of the light portals comprise slotted recesses.

### Claim 48 (depends on 47)

The device as claimed in claim 47, wherein the thread comprises conforming engagement pieces at either end thereof for attaching the device to an adjacent device.

### Claim 49 (depends on 44)

The device as claimed in claim 44, wherein the device comprises a spool of the thread.

### Claim 50 (depends on 49)

The device as claimed in claim 49, wherein the spool is internally located.

### Claim 51 (depends on 50)

The device as claimed in claim 50, wherein the spool is located within one of the light portals.

### Claim 52 (depends on 51)

The device as claimed in claim 51, wherein the spool is wound one around a collar at the midsection.

### Claim 53 (depends on 52)

The device as claimed in claim 52, wherein the spool is covered with a removable layer.

### Claim 54 (depends on 52)

The device as claimed in claim 52, wherein the thread comprises ingestion depth markings therealong.
