Systems and methods for an absorbance detector with optical reference
AssigneePhoseon Technology, Inc.
InventorsLowell Brunson, John Christopher Freitag, Theresa Thompson
Life of this patent
Estimating the term…
Abstract
Systems and methods are provided for a UV-VIS spectrophotometer, such as a UV-VIS detector unit included in a high-performance liquid chromatography system. In one example, a system for the UV-VIS detector unit may include a first light source, a signal detector, a flow path positioned intermediate the first light source and the signal detector, a second light source, and a reference detector. The first light source, the signal detector, and the flow path may be aligned along a first axis, and the second light source and the reference detector may be aligned along a second axis, different than the first axis.
Claims20
A system comprising:
- a light source;
- a signal detector;
- a flow path positioned intermediate the light source and the signal detector;
- and
- a reference detector housed in a common housing with the light source, wherein the reference detector is configured to detect light reflected from the housing and/or components within the housing.
A system, comprising:
- a light source mounted on a substrate;
- a signal detector;
- a flow path positioned intermediate the light source and the signal detector, where the light source, the signal detector, and the flow path are aligned along a common axis;
- a reference detector mounted on the substrate;
- and a reflector positioned to direct light from the light source to the reference detector, the reflector positioned off-axis from the common axis.
A system, comprising:
- a light source;
- a signal detector;
- a flow path positioned intermediate the light source and the signal detector, the flow path configured to flow a sample;
- coupling optics positioned intermediate the light source and the flow path;
- a reference detector positioned to detect light reflected from the coupling optics;
- and a controller configured to:
- determine a sample transmittance signal based on output from the signal detector;
- determine a reference signal based on output from the reference detector;
- and
- calculate an absorbance of the sample based on the sample transmittance signal and the reference signal.
Dependencies are inferred from the claim text.