# US 2023/0054072 A1 · Peritoneal dialysis cassette

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- Number: US 2023/0054072 A1
- Document ID: US20230054072A1
- Status: Published application
- Kind: A1
- Application number: 17/406,848
- Filed: 2021-08-19
- Published: 2023-02-23
- Earliest claimed: 2021-08-19
- Assignees: Medtronic, Inc.
- Applicants: Medtronic, Inc.
- Inventors: Rajkumar Vp; Rathnakara Narayana; Vikas Chitradurga Mruthyunjaya
- Web page: https://patentgrep.com/patent/US20230054072A1

## CPC

- A61M 1/159: {specially adapted for peritoneal dialysis}
- A61M 1/1524: {the interface providing means for actuating on functional elements of the cassette, e.g. plungers}
- A61M 1/154: {with sensing means or components thereof}
- A61M 1/1561: {at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil}
- A61M 1/1565: {Details of valves}
- A61M 1/28: Peritoneal dialysis {; Other peritoneal treatment, e.g. oxygenation}
- A61M 2205/12: with interchangeable cassettes forming partially or totally the fluid circuit
- A61M 2205/121: interface between cassette and base
- A61M 2205/127: with provisions for heating or cooling
- A61M 2205/3331: Pressure; Flow
- A61M 2205/3368: Temperature
- A61M 2210/1017: Peritoneal cavity
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

An example article includes a rigid member defining a plurality of fluid flow paths and a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the respective lumen and unoccluded in the absence of the externally applied pressure. Each flexible tube is configured to be fluidically connected to a flow path of the plurality of flow paths, and different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes.

## Claims

### Claim 1

An article comprising:
a rigid member defining a plurality of fluid flow paths; and
a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the respective lumen and unoccluded in the absence of the externally applied pressure,
wherein each flexible tube is configured to be fluidically connected to a flow path of the plurality of flow paths,
wherein different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes.

### Claim 2 (depends on 1)

The article of claim 1, wherein each flexible tube of the plurality of flexible tubes is configured to be occluded via at least one of a mechanical, pneumatic, or mechanical and pneumatic actuator configured to collapse the lumen.

### Claim 3 (depends on 1)

The article of claim 1, wherein the externally applied pressure is greater than or equal to 10 newtons (N) and less than or equal to 15N.

### Claim 4 (depends on 1)

The article of claim 1, further comprising at least one of a temperature sensor or a pressure sensor configured to sense a temperature or a pressure, respectively, of fluid in at least one flow path of the plurality of flow paths.

### Claim 5 (depends on 1)

The article of claim 1, wherein the rigid member comprises a first rigid member and a second rigid member connected together, each of the first and second rigid members defining a plurality of channels that form the plurality of fluid flow paths when the first and second rigid members are connected together.

### Claim 6 (depends on 5)

The article of claim 5, wherein the first rigid member and the second rigid member are connected together via at least one of laser welding, ultrasonic welding, or hot plate welding.

### Claim 7 (depends on 1)

The article of claim 1, wherein the rigid member further defines a plurality of fluidic connectors, each fluidic connector of the plurality of fluidic connectors being fluidically connected to a flow path of the plurality of fluid flow paths, wherein each flexible tube of the plurality of flexible tubes is configured to be connected to a respective fluidic connector by at least one of a friction fit or a heat seal.

### Claim 8 (depends on 1)

The article of claim 1, wherein the plurality of fluid flow paths is less than or equal to ten fluid flow paths configured to selectively interconnect a plurality of external fluid connections, the plurality of external fluid connections comprising at least one patient fluid connection, at least one dialysate fluid connection, at least one drain fluid connection, and at least one fluid heating fluid connection.

### Claim 9

A system comprising:
a cassette comprising:
a rigid member defining a plurality of fluid flow paths, each of the fluid flow paths including at least one fluidic connection to a fluid input or fluid output of the rigid member; and
a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the lumen and unoccluded in the absence of the externally applied pressure,
wherein each flexible tube is configured to be fluidically connected to a flow path of the plurality of fluid flow paths,
wherein different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes;
a peritoneal dialysis device comprising a plurality of actuators configured to apply the pressure externally to the plurality of flexible tubes; and
control circuitry configured to selectively cause one or more actuators of the plurality of actuators to apply the pressure to or release the pressure from one or more flexible tubes of the plurality of flexible tubes.

### Claim 10 (depends on 9)

The system of claim 9, further comprising:
a compressor configured to provide air to the plurality of actuators; and
a pneumatic pump configured to move fluid through the plurality of fluid flow paths, wherein the plurality of actuators are pneumatic actuators, wherein the compressor is configured to provide less than 3000,000 Pascals (Pa) of pressure to the plurality of pneumatic actuators and the pneumatic pump.

### Claim 11 (depends on 9)

The system of claim 9, wherein the plurality of actuators comprises at least one of a mechanical actuator, a pneumatic actuator, or a mechanical and pneumatic actuator.

### Claim 12 (depends on 9)

The system of claim 9, wherein the cassette further comprises at least one of a temperature sensor or a pressure sensor configured to sense a temperature or a pressure, respectively, of fluid in at least one flow path of the plurality of flow paths.

### Claim 13 (depends on 9)

The system of claim 9, wherein the rigid member comprises a first rigid member and a second rigid member connected together, each of the first and second rigid members defining a plurality of channels that form the plurality of fluid flow paths when the first and second rigid members are connected together.

### Claim 14 (depends on 13)

The system of claim 13, wherein the first rigid member and the second rigid member are connected together via at least one of laser welding, ultrasonic welding, or hot plate welding.

### Claim 15 (depends on 9)

The system of claim 9, wherein the rigid member further includes a first connector and a second connector configured to fluidically connect respective flexible tubes of the plurality of flexible tubes to the rigid member, wherein the flexible tubes are configured to mechanically connect to the first end connector and the second end connector by at least one of a friction fit or a heat seal.

### Claim 16 (depends on 9)

The system of claim 9, wherein the plurality of fluid flow paths is less than or equal to ten fluid flow paths configured to selectively interconnect a plurality of external fluid connections, the plurality of external fluid connections comprising at least one patient fluid connection, at least one dialysate fluid connection, at least one drain fluid connection, and at least one fluid heating fluid connection.

### Claim 17 (depends on 9)

The system of claim 9, wherein the control circuitry is configured to select and form one flow path of the plurality of flow paths via causing a first set of actuators of the plurality of actuators to occlude a corresponding first set of flexible tubes and causing a second set of actuators to unocclude a second set of flexible tubes, wherein the first set of actuators and the first set of flexible tubes are different from the second set of actuators and the second set of flexible tubes.

### Claim 18

A method comprising:
selecting, via control circuitry, a fluid flow path of a plurality of fluid flow paths defined by a peritoneal dialysis cassette, the peritoneal dialysis cassette comprising:
a rigid member defining a plurality of fluid flow paths, each of the fluid flow paths including at least one fluidic connection to a fluid input or fluid output of the rigid member; and
a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the respective tube and unoccluded in the absence of the externally applied pressure,
wherein each flexible tube of the plurality of flexible tubes is configured to be fluidically connected to a flow path of the rigid member,
wherein different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes; and
causing, via the control circuitry, one or more actuators to occlude at least one flexible tube of the plurality of flexible tubes to define the fluid flow path.

### Claim 19 (depends on 18)

The method of claim 18, wherein the one or more actuators is a first set of actuators and the at least one flexible tube comprises at least one first flexible tube, the method further comprising causing, via the control circuitry, at least one second actuator to unocclude a second flexible tube to define the fluid flow path.

### Claim 20 (depends on 19)

The method of claim 19, wherein the fluid flow path is a first fluid flow path, the method further comprising:
selecting, via the control circuitry, a second fluid flow path different from the first fluid flow path; and
forming the second fluid flow path by at least:
causing, via the control circuitry, the second actuator to occlude the second flexible tube; and
causing, via the control circuitry, an actuator different from the second actuator to unocclude a flexible tube different from the second flexible tube.
