# US 2023/0053633 A1 · Clot retrieval system for removing occlusive clot from a blood vessel

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- Number: US 2023/0053633 A1
- Document ID: US20230053633A1
- Status: Published application
- Kind: A1
- Application number: 17/968,399
- Filed: 2022-10-18
- Published: 2023-02-23
- Earliest claimed: 2014-03-11
- Assignees: Neuravi Limited
- Applicants: Neuravi Limited
- Inventors: Michael GILVARRY; David VALE; Brendan CASEY; Kevin McARDLE; Jacqueline O'GORMAN
- Web page: https://patentgrep.com/patent/US20230053633A1

## CPC

- A61B 17/221: Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)}
- A61B 2017/2212: {having a closed distal end, e.g. a loop}
- A61B 2217/005: with suction drainage system
- A61M 2025/0042: {Microcatheters, cannula or the like having outside diameters around 1 mm or less}
- A61M 2025/0681: {Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube}
- A61M 2039/1077: {Adapters, e.g. couplings adapting a connector to one or several other connectors}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A clot retrieval device comprising an elongate shaft having a proximal end and a distal end and a clot retrieval element at the distal end of the elongate shaft. A proximal end of the elongate shaft configured to retract a first catheter over the elongate shaft. The shaft extension member comprising one or more raised profiles configured to interfere with one or more indentations along the elongate shaft such that the shaft extension member is configured to extend between a first length and an intermediate length. A second catheter is advanced to or adjacent to the distal end of the clot retrieval device shaft to enable enhanced aspiration adjacent to the clot retrieval element.

## Claims

### Claim 1

A clot retrieval device comprising:
an elongate shaft having a proximal end, a distal end, and a shaft extension member;
a clot retrieval element at the distal end of the elongate shaft,
a proximal end of the elongate shaft configured to retract a first catheter over the elongate shaft,
the shaft extension member comprising one or more raised profiles configured to interfere with one or more indentations along the elongate shaft such that the shaft extension member is configured to extend between a first length and an intermediate length; and
a second catheter being advanceable to or adjacent to the distal end of the elongate shaft for enhanced aspiration adjacent to the clot retrieval element.

### Claim 2 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein a first indentation along the elongate shaft is configured to allow a first raised profile on the shaft extension member to pass by in a distal direction, thereby extending the shaft extension member between the first length and the intermediate length.

### Claim 3 (depends on 2)

The clot retrieval device as claimed in claim 2, wherein a second indentation along the elongate shaft is configured to prevent a second raised profile on the shaft extension member to pass by in a distal direction, thereby preventing the shaft extension member from extending beyond a final length,
wherein the second indentation is positioned distal the first indentation.

### Claim 4 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein aspiration is delivered through the second catheter, a lumen of the second catheter being larger than a lumen of the first catheter.

### Claim 5 (depends on 4)

The clot retrieval device as claimed in claim 4, wherein the first catheter comprises a microcatheter through which the clot retrieval device is delivered and the second catheter is an intermediate catheter.

### Claim 6 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein the proximal end of the elongate shaft is adapted for retraction of the first catheter having a lumen and subsequent advancement of the second catheter having a lumen, wherein the lumen of the second catheter is larger than the lumen of the first catheter.

### Claim 7 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein the proximal end of the elongate shaft is adapted for retraction and removal of the first catheter having a lumen through the second catheter.

### Claim 8 (depends on 1)

The clot retrieval device as claimed in claim 1, further comprising: an adaptor at the proximal end of the elongate shaft of the clot retrieval device, the adaptor being adapted to receive the shaft extension member.

### Claim 9 (depends on 8)

The clot retrieval device as claimed in claim 8, wherein the adaptor is integral with the clot retrieval device shaft proximal end, and wherein the adaptor comprises a receiver which is adapted to receive the shaft extension member.

### Claim 10 (depends on 8)

The clot retrieval device as claimed in claim 8, wherein the adaptor is releasably mountable to the proximal end of the elongate shaft.

### Claim 11 (depends on 10)

The clot retrieval device as claimed in claim 10, wherein the adaptor comprises a mounting section for mounting to the proximal end of the shaft and a receiver which is adapted to receive the shaft extension member.

### Claim 12 (depends on 11)

The clot retrieval device as claimed in claim 11, wherein the mounting section is a push fit with the proximal end of the elongate shaft, and wherein the receiver is a push fit with the shaft extension member.

### Claim 13 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein the elongate shaft has at least one tactile feature at or adjacent to the proximal end thereof.

### Claim 14 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein the clot retrieval device shaft has at least one high friction feature at or adjacent to the proximal end thereof.

### Claim 15 (depends on 1)

The clot retrieval device as claimed in claim 1, wherein one or both of the proximal end and the extension member comprises at least one stop to set the length to which the extension member may extend from the tubular proximal end and/or to control the degree of push that applicable to the extension member.

### Claim 16 (depends on 1)

A clot retrieval system comprising:
a clot retrieval device as claimed in claim 1; and
an adaptor for mounting to the proximal end of the elongate shaft of the clot retrieval device.

### Claim 17 (depends on 16)

The clot retrieval system as claimed in claim 16, wherein the adaptor comprises a mounting section for mounting to the proximal end of the clot retrieval device shaft and a receiver which is adapted to receive the shaft extension member, and wherein the adaptor mounting section is a push fit with the proximal end of the clot retrieval shaft.

### Claim 18 (depends on 17)

The clot retrieval system as claimed in claim 17, wherein the adaptor receiver is a push fit with the shaft extension member, and/or wherein the adaptor is configured to accept the proximal end of a standard guidewire.

### Claim 19

A method for retrieving a clot from a vasculature comprising:
positioning a second catheter over a first catheter;
providing a clot retrieval device comprising an elongate shaft comprising one or more indentations and a shaft extension member comprising one or more raised profiles;
pushing the shaft extension member such that the one or more raised profiles interferes with the one or more indentations, thereby extending the shaft extension member between a first length and an final length;
deploying the clot retrieval device from the first catheter; and
retracting the first catheter over the shaft and maintaining control of a proximal end of the shaft.

### Claim 20 (depends on 19)

The method as claimed in claim 19, further comprising:
applying aspiration to the clot through a lumen of the second catheter after retraction of the first catheter over the clot retrieval device elongate shaft,
wherein the first catheter is a delivery catheter for the clot retrieval device and the method further comprises deploying the clot retrieval device from the delivery catheter and subsequently retracting the delivery catheter over the clot retrieval device shaft.
