Electrostatically gated nanofluidic membranes for control of molecular transport
AssigneeThe Methodist Hospital System
InventorsAlessandro Grattoni, Xuewu Liu, Mauro Ferrari
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AssigneeThe Methodist Hospital System
InventorsAlessandro Grattoni, Xuewu Liu, Mauro Ferrari
Estimating the term…
Devices and methods for controlling molecular transport are disclosed herein. The devices include a membrane having a plurality of nanochannels extending therethrough. The membrane has an inner electrically conductive layer and an outer dielectric layer. The outer dielectric layer creates an insulative barrier between the electrically conductive layer and the contents of the nanochannels. At least one electrical contact region is positioned on a surface of the membrane. The electrical contact region exposes the electrically conductive layer of the membrane for electrical coupling to external electronics. When the membrane is at a first voltage, molecules flow through the nanochannels at a first release rate. When the membrane is at a second voltage, charge accumulation within the nanochannels modulates the flow of molecules through the nanochannels to a second release rate that is different than the first release rate. Methods of fabricating devices for controlling molecular transport are also disclosed herein.
A device for controlling molecular transport, the device comprising;
A method of fabricating a device for controlling molecular transport, the method comprising:
A method of controlling the delivery of a therapeutic substance through a membrane, the method comprising:
Dependencies are inferred from the claim text.